CCR5 adopts three homodimeric conformations that control cell surface delivery
CCR5 delivery to the cell surface.
CCR5 delivery to the cell surface.
Maraviroc (MVC) is an allosteric CCR5 inhibitor used against HIV-1 infection.
Maraviroc is a nonpeptidic small molecule human immunodeficiency virus type 1 (HIV-1) entry inhibitor that has just entered the therapeutic arsenal for the treatment of patients.
CC chemokine receptor 5 (CCR5) is a G-protein-coupled receptor for the chemokines CCL3, -4, and -5 and a coreceptor for entry of R5-tropic strains of human immunodeficiency virus …
The chemokine CXCL12 and the receptor CXCR4 play pivotal roles in normal vascular and neuronal development, in inflammatory responses, and in infectious diseases and cancer.