Bihel, F.
Chemical Space

Scaffold-Based Libraries Versus Make-on-Demand Space: A Comparative Assessment of Chemical Content.

The scaffold-based and the reaction-based approaches to virtual library creation, analyzed here using ≈1.5 million amide and sulfonamide products, generate distinct ensembles when …

Bui, L.
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Small Molecule Libraries/Chemistry/Chemical Synthesis/Pharmacology

The IMS Library: from IN-Stock to Virtual.

A chemical library is a key element in the early stages of pharmaceutical research.

Djikic-Stojsic, T.
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Drug Design

Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.

Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase, taking part in the activation pathway of the pro-inflammatory transcription factor NF-kB and is demonstrating a …

Bollenbach, M.
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