Colin, P. | Chemogenomics Structural Group

Targeting of specific CCR5-G protein complexes underlies biased signaling by HIV-1 envelope glycoproteins.

CCR5 exists in a mosaic of distinct membrane-associated functional states, differentially accessed by viral and endogenous ligands. This spatial and signaling compartmentalization …

Gasser, R.

• Nov 24, 2025 • 1 min read

Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor.

The chemokine receptor CCR5 is a key player in HIV-1 infection.

Jacquemard, C.

• Jul 18, 2021 • 1 min read

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity

Maraviroc (MVC) is an allosteric CCR5 inhibitor used against HIV-1 infection.

Garcia-Perez, J.

• Jun 18, 2015 • 1 min read