Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor.
The chemokine receptor CCR5 is a key player in HIV-1 infection.
The chemokine receptor CCR5 is a key player in HIV-1 infection.
The high demand of the pharmaceutical industry for new modalities to address the diversification of biological targets with large surfaces of interaction led us to investigate the …
Over the past decade, the ever-growing structural information on G-protein coupled receptors (GPCRs) has revealed the three-dimensional (3D) characteristics of a receptor structure …
CCR5 delivery to the cell surface.