Krier, M.

Assessing the Scaffold Diversity of Screening Libraries

Medicinal chemists have traditionally realized assessments of chemical diversity and subsequent compound acquisition, although a recent study suggests that experts are usually …

Krier, M.

Design of Small-Sized Libraries by Combinatorial Assembly of Linkers and Functional Groups to a Given Scaffold: Application to the Structure-Based Optimization of a Phosphodiesterase 4 Inhibitor

Combinatorial chemistry and library design have been reconciled by applying simple medicinal chemistry concepts to virtual library design.

Krier, M.