CCR5 exists in a mosaic of distinct membrane-associated functional states, differentially accessed by viral and endogenous ligands. This spatial and signaling compartmentalization …
The chemokine receptor CCR5 is a key player in HIV-1 infection.
CCR5 delivery to the cell surface.
Maraviroc (MVC) is an allosteric CCR5 inhibitor used against HIV-1 infection.
Maraviroc is a non-peptidic, low molecular weight CC chemokine receptor 5 (CCR5) ligand that has recently been marketed for the treatment of HIV infected individuals.
Maraviroc is a nonpeptidic small molecule human immunodeficiency virus type 1 (HIV-1) entry inhibitor that has just entered the therapeutic arsenal for the treatment of patients.
CC chemokine receptor 5 (CCR5) is a G-protein-coupled receptor for the chemokines CCL3, -4, and -5 and a coreceptor for entry of R5-tropic strains of human immunodeficiency virus …
The chemokine CXCL12 and the receptor CXCR4 play pivotal roles in normal vascular and neuronal development, in inflammatory responses, and in infectious diseases and cancer.