Use of fluorescence polarization to monitor MHC-peptide interactions in solution.
We describe here fluorescence polarization-based methods to investigate class I MHC-peptide interactions in solution.
We describe here fluorescence polarization-based methods to investigate class I MHC-peptide interactions in solution.
Combining virtual screening with biophysical studies of protein-ligand complexes is an effective tool for designing new peptidomimetics.
Designing synthetic vaccines from class I major histocompatibility complex (MHC)-binding antigenic peptides requires not only knowledge of the binding affinity of the designed …