Scapozza, L. | Chemogenomics Structural Group

Molecular dynamics and structure-based drug design for predicting non-natural nonapeptide binding to a class I MHC protein

Starting from the known three-dimensional structure of the class I major histocompatibility complex-encoded HLA-B*2705 protein, three non-natural nonapeptides were designed to fit …

Scapozza, L.

• Jul 1, 1995 • 1 min read

Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen

From the three-dimensional structure of the class I major histocompatibility complex (MHC) HLA-B*2705 protein, several nonnatural peptides were designed either to optimize the …

Rognan, D.

• Jan 31, 1995 • 1 min read

Molecular Dynamics Simulation of MHC-Peptide Complexes as a Tool for Predicting Potential T Cell Epitopes

The class I major histocompatibility complex-encoded HLA-B*2705 protein was simulated in complex with six different peptides exhibiting unexpected structure-activity relationships.

Rognan, D.

• Sep 27, 1994 • 1 min read