Schalon, C.

Binding of Protein Kinase Inhibitors to Synapsin I Inferred from Pair-Wise Binding Site Similarity Measurements

Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages.

Franchi, E. D.

How to measure the similarity between protein ligand-binding sites?

Quantification of local similarity between protein 3D structures is a promising tool in computer-aided drug design and prediction of biological function.

Kellenberger, E.

A simple and fuzzy method to align and compare druggable ligand-binding sites

A novel method to measure distances between druggable protein cavities is presented.

Schalon, C.

sc-PDB:  an Annotated Database of Druggable Binding Sites from the Protein Data Bank

The sc-PDB is a collection of 6 415 three-dimensional structures of binding sites found in the Protein Data Bank (PDB).

Kellenberger, E.