Traiffort, E.

Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling

Background and Purpose The transmembrane protein LINGO-1 is a negative regulator in the nervous system mainly affecting axonal regeneration, neuronal survival, oligodendrocyte …

Cobret, L.

Functional Characterization of Sonic Hedgehog Mutations Associated with Holoprosencephaly

Mutations of the developmental gene Sonic hedgehog (SHH) and alterations of SHH signaling have been associated with holoprosencephaly (HPE), a rare disorder characterized by a …

Traiffort, E.