sc-PDB: a database for identifying variations and multiplicity of ‘druggable’ binding sites in proteins
The sc-PDB database is an annotated archive of druggable binding sites extracted from the Protein Data Bank.
The sc-PDB database is an annotated archive of druggable binding sites extracted from the Protein Data Bank.
CC chemokine receptor 5 (CCR5) is a G-protein-coupled receptor for the chemokines CCL3, -4, and -5 and a coreceptor for entry of R5-tropic strains of human immunodeficiency virus …
Schistosomiasis is a major tropical parasitic disease.
Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages.
Inferring the biological function of a protein from its three-dimensional structure as well as explaining why a drug may bind to various targets is of crucial importance to modern …
Chemogenomics is an emerging interdisciplinary field aiming at identifying all possible ligands of all possible targets.
Background A greater reduction in cardiovascular risk and vascular protection associated with diet rich in polyphenols are generally accepted; however, the molecular targets for …
The metabolic stability and selectivity of a series of CCR8 antagonists against binding to the hERG ion channel and cytochrome Cyp2D6 are studied by principal component analysis.
GPRC6A displays high sequence homology to the Ca2+-sensing receptor (CaSR).
Pyochelin (Pch) and enantio-pyochelin (EPch) are enantiomer siderophores that are produced by Pseudomonas aeruginosa and Pseudomonas fluorescens, respectively, under iron …