Binding Properties of Pyochelin and Structurally Related Molecules to FptA of Pseudomonas aeruginosa
Pyochelin (Pch) is a siderophore that is produced in iron‐limited conditions, by both Pseudomonas aeruginosa and Burkholderia cepacia.
Pyochelin (Pch) is a siderophore that is produced in iron‐limited conditions, by both Pseudomonas aeruginosa and Burkholderia cepacia.
Nevirapine (Viramune®) belongs to the first generation of non-nucleoside reverse transcriptase inhibitors (NNRTIs).
The sc-PDB is a collection of 6 415 three-dimensional structures of binding sites found in the Protein Data Bank (PDB).
The concomitant development of in silico screening technologies and of three-dimensional information on therapeutically relevant macromolecular targets makes it possible to …
Medicinal chemists have traditionally realized assessments of chemical diversity and subsequent compound acquisition, although a recent study suggests that experts are usually …
The structural reorganizations occurring on the nicotinic acetylcholine receptor (nAChR) during activation and subsequent desensitization have been investigated through …
The amino acid sequences of 369 human nonolfactory G-protein-coupled receptors (GPCRs) have been aligned at the seven transmembrane domain (TM) and used to extract the nature of 30 …
The Ca2+-sensing receptor (CaSR) belongs to the class III G-protein-coupled receptors (GPCRs), which include receptors for pheromones, amino acids, sweeteners, and the …
ADP-ribosyl cyclases are structurally conserved enzymes that are best known for catalyzing the production of the calcium-mobilizing metabolite, cyclic adenosine diphosphate ribose …
Zinc fingers are small structured protein domains that require the coordination of zinc for a stable tertiary fold.