Synergistic Use of Virtual Screening and Biophysical Methods for the Protein-Based Design of Peptidomimetics
Nov 1, 2000·
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Rognan, D.
Bissantz, C.
Dédier, S.
Logean, A.
Reinelt, S.
Abstract
Combining virtual screening with biophysical studies of protein-ligand complexes is an effective tool for designing new peptidomimetics. When a three-dimensional structure of the target protein is known, automated docking of chemical databases can be used as a powerful filter to reduce
Type
Publication
Synergistic Use of Virtual Screening and Biophysical Methods for the Protein-Based Design of Peptidomimetics, CHIMIA International Journal for Chemistry 2000 54 (11), 658-662