Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways.
G protein-coupled receptors (GPCRs) constitute a functionally diverse protein family and are targets for a broad spectrum of pharmaceuticals.
G protein-coupled receptors (GPCRs) constitute a functionally diverse protein family and are targets for a broad spectrum of pharmaceuticals.
Protein-protein interfaces represent challenging but very promising targets to discover novel drugs with exquisite specificity profiles.