Structure-Based Approaches to Target Fishing and Ligand Profiling
Chemogenomics is an emerging interdisciplinary field aiming at identifying all possible ligands of all possible targets.
Chemogenomics is an emerging interdisciplinary field aiming at identifying all possible ligands of all possible targets.
A novel method to measure distances between druggable protein cavities is presented.
Paradigms in drug design and discovery are changing at a significant pace.
The concomitant development of in silico screening technologies and of three-dimensional information on therapeutically relevant macromolecular targets makes it possible to …