Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival
NAD, a key co-enzyme required for cell metabolism, is synthesized via two pathways in most organisms.
NAD, a key co-enzyme required for cell metabolism, is synthesized via two pathways in most organisms.
Bovine CD38/NAD+glycohydrolase (bCD38) catalyses the hydrolysis of NAD+ into nicotinamide and ADP-ribose and the formation of cyclic ADP-ribose (cADPR).